Cellular models isolated from fresh cultures are essential for the advancement of biomedical research. It is well known that hepatocytes are used in biomedical research because of their metabolism abilities; which allows the classification, diagnosis, prognosis and treatment of human disease, as well as the evaluation of therapeutic response to drugs. For this reason, hepatocytes acquisition is now a critical step for research activities.
Hepatocytes are commonly used in drug discovery and preclinical drug development to perform experiments requiring intact cellular systems. Intact hepatocytes contain the major hepatic drug-metabolizing enzymes required to study the four categories of xenobiotic biotransformation: hydrolysis, reduction, oxidation and conjugation.
Researchers face many challenges in this area, not least of which being the legal and ethical issues around sourcing tissue/cells , but also the practical challenge of sourcing quality specimens that are fit for use in a diverse range of analytical processes.
Cytes Biotechnologies, SL. has developed liver cell solutions by providing high quality, fully characterized specimens in order to promote the development of biomedical research.