Fresh Human Primary Hepatocytes

Cytes Biotechnologies, S.L. offers the hepatocytes in various formats (Male/Female):

Fresh Cold-Stored Suspension
Fresh 6/12/24/48/96-well (Overlay or Non-Overlay)
Other formats: customised isolations*, cells used for internal projects


Hepatocytes in suspension are preferable for short term studies whereas plated hepatocytes are more useful for long-term orientated studies.


Fresh human primary hepatocytes are used for several studies:
 

Cell Metabolism:

  • Metabolic pathway identification and profiling
  • Metabolism of stable compounds
  • Determination of metabolic routes in metabolite formation
  • Assessment of effects on cell function

 

 Drug Development:

  • Drug-drug interaction
  • Evaluation of drug metabolism
  • Drug-mediated responses

 
Toxicity:
  • Toxicity studies
  • Hepatotoxicity
  • Detoxification effects
  • Uptake and efflux transporter activities 

Other studies:
  • Assessment of potential enzyme induction or inhibition

* Healthy or pathological ttissue according to client needs