​Home > Human Non Parenchymal Cells

CYTES PRIMARY HUMAN HEPATOCYTES 

COMMON USES

- Metabolism analysis

- Drug development

- Toxicity assessments

- Enzyme activity studies

- Among others

DOCUMENTATION

CYTES PRODUCTS

Human Non Parenchymal Cells

Non-parenchymal cells (NPCs) isolation enables the possibility to obtain liver models mimicking the microenvironment and microanatomy of the human liver for the study of liver functions. Moreover, these models present organotypic hepatocyte-NPC interactions via direct contact or paracrine signalling. Therefore, these models are able to recreate the physiological in vivo environment and this is a fundamental requirement to obtain a specific predictive response for the study of liver physiology/pathology or to perform new drug screenings and safety analysis with a high predictive value.

PRIMARY HUMAN HEPATOCYTES AVAILABLE

You can directly check Cytes Biotechnologies Primary Human Hepatocytes on the inventory table below.

CYTES PRIMARY HUMAN HEPATOCYTES 

COMMON USES

- Metabolism analysis

- Drug development

- Toxicity assessments

- Enzyme activity studies

DOCUMENTATION

HUMAN NON-PARENCHYMAL CELLS MIX STOCK 

Use filters on the table to find the best lot for your needs. Use the "export option" in the top right corner to export data (it can be exported table by table (excel) or all together (PDF, HTML)). See videos below for further information.  

  • 3D/Spheroid Qualified: Lot tested positively for 3D culture (Spheroids)
  • 24/96 Well Qualified: Plateable in 24/96 well plate
  • Days in culture 24w: Keep monolayer and good morphology in 24 well plate under proper conditions

You can order or receive more information about Cytes Biotechnologies Non-Parenchymal Cells lots here

STELLATE CELLS STOCK

Use filters on the table to find the best lot for your needs. Use the "export option" in the top right corner to export data (it can be exported table by table (excel) or all together (PDF, HTML)). See videos below for further information.  

  • 3D/Spheroid Qualified: Lot tested positively for 3D culture (Spheroids)
  • 24/96 Well Qualified: Plateable in 24/96 well plate
  • Days in culture 24w: Keep monolayer and good morphology in 24 well plate under proper conditions

You can order your Primary Human Hepatocytes lots here

OnBording Videos 

Inventory Filters Use 

Inventory Export Options 

Obtain personalized advice from Cytes Scientific and Sales experts 

At Cytes Biotechnologies we will personally advise you to obtain the liver cells that best suit the conditions of your project. 

From the moment you contact us, our experts will follow the following steps

  1. Detailed study of the requirements described on the form 
  2. Personalized advice according to the needs of each client. 
  3. Permanent contact throughout the process to ensure the best results


Fill in the following form and we will contact you with an answer to your request. 

            HUMAN NON PARENCHYMAL CELLS

      Information Request 

Kupffer Cells 

Kupffer cells are the specialized macrophages residents in the liver, lining the walls of the sinusoids. 

These cells are part of the mononuclear phagocytes system and can be activated to produce inflammatory cytokines, growth factors and reactive oxygen species.

Contact

Hepatic Stellate Cells 

Stellate cells are the major cell type involved in liver fibrosis in response to liver injury and they play a key role in the homeostasis of liver extracellular matrix, repair, regeneration and fibrosis, and control retinol metabolism, storage and release.

Inventory
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Liver Endothelial Cells

The liver contains two distinct endothelial cell types: vascular (LEC) and sinusoidal (LSEC). 
Liver Endothelial cells (LEC) are highly specialized endothelial cells representing the interface between blood cells and the rest of liver cells. Liver Sinusoidal Endothelial cells (LSEC) are microvascular endothelial cells which, in physiological conditions, regulate hepatic vascular tone contributing to the maintenance of a low portal pressure during digestion.
Contact

NPC's Mix

Hepatic non-parenchymal cells (NPCs) represent about 30% of the liver and are specialized cells which interact with hepatocytes for several functions. For this reason, liver co-cultures may increase the sensitivity of liver models for ADME/Tox-related research by recapitulating the complexity of a whole liver. 


"Mix NPCs" provides a mix of different types of liver cells, including Kupffer cells, liver endothelial cells and Stellate cells.
Inventory
Contact
MSDS
CoA
Protocols
MSDS
CoA
Protocols
Non Parenchymal Cells

Non Parenchymal Cells

Non-parenchymal cells (NPCs) isolation enables the possibility to obtain liver models mimicking the microenvironment and microanatomy of the human liver for the study of liver functions. Moreover, these models present organotypic hepatocyte-NPC interactions via direct contact or paracrine signalling. Therefore, these models are able to recreate the physiological in vivo environment and this is a fundamental requirement to obtain a specific predictive response for the study of liver physiology/pathology or to perform new drug screenings and safety analysis with a high predictive value.


Cell types:

-Kupffer cells
-Stellate cells
-Liver Endothelial cells
MSDS
CoA
Protocols
MSDS
CoA
Protocols
Non Parenchymal Cells

Non Parenchymal Cells

Non-parenchymal cells (NPCs) isolation enables the possibility to obtain liver models mimicking the microenvironment and microanatomy of the human liver for the study of liver functions. Moreover, these models present organotypic hepatocyte-NPC interactions via direct contact or paracrine signalling. Therefore, these models are able to recreate the physiological in vivo environment and this is a fundamental requirement to obtain a specific predictive response for the study of liver physiology/pathology or to perform new drug screenings and safety analysis with a high predictive value.

Cell types:

-Kupffer cells
-Stellate cells

-Endothelial cells

Kupffer Cells 

Kupffer cells are the specialized macrophages residents in the liver, lining the walls of the sinusoids. 

These cells are part of the mononuclear phagocytes system and can be activated to produce inflammatory cytokines, growth factors and reactive oxygen species.

Inventory
Contact

Hepatic Stellate Cells 

Ready-to-use media designed for plating cryopreserved human hepatocytes providing an optimal attachement and monolayer formation. 


Contact

Endothelial Cells

The liver contains two distinct endothelial cell types: vascular (LEC) and sinusoidal (LSEC). 
Liver Endothelial cells (LEC) are highly specialized endothelial cells representing the interface between blood cells and the rest of liver cells. Liver Sinusoidal Endothelial cells (LSEC) are microvascular endothelial cells which, in physiological conditions, regulate hepatic vascular tone contributing to the maintenance of a low portal pressure during digestion.


Contact

 Mix NPC's

Hepatic non-parenchymal cells (NPCs) represent about 30% of the liver and are specialized cells which interact with hepatocytes for several functions. For this reason, liver co-cultures may increase the sensitivity of liver models for ADME/Tox-related research by recapitulating the complexity of a whole liver. 

"Mix NPCs" provides a mix of different types of liver cells, including Kupffer cells, liver endothelial cells and Stellate cells.
Inventory
Contact